Article
Genetic diversity of Plasmodium vivax reticulocyte binding protein 2b in global parasite populations.
Parasites & vectors - 13 Jun 2022
Zhang Xuexing, Wei Haichao, Zhang Yangminghui, Zhao Yan, Wang Lin, Hu Yubing, Nguitragool Wang, Sattabongkot Jetsumon, Adams John, Cui Liwang, Cao Yaming, Wang Qinghui
Abstract excerpt
BACKGROUND: Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) plays a critical role in parasite invasion of reticulocytes by binding the transferrin receptor 1. PvRBP2b is a vaccine candidate based on the negative correlation between antibody titers against PvRBP2b recombinant proteins and parasitemia and risk of vivax malaria. The aim of this study was to analyze the genetic diversity of the PvRBP2b...
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