Article
Natural genetic diversity of the DBL domain of a novel member of the Plasmodium vivax erythrocyte binding-like proteins (EBP2) in the Amazon rainforest.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2024
Fernandes Gabriela M, Rodrigues-Mattos Guilherme H, Torres Letícia M, Guedes Karla S, Fontes Cor J F, Ntumngia Francis B, Adams John H, Brito Cristiana F A, Kano Flora S, de Sousa Taís N, Carvalho Luzia H
Abstract excerpt
In malaria parasites, the erythrocyte binding-like proteins (EBL) are a family of invasion proteins that are attractive vaccine targets. In the case of Plasmodium vivax, the widespread malaria parasite, blood-stage vaccines have been largely focused on a single EBL candidate, the Duffy binding-like domain (DBL) of the Duffy binding protein (DBPII), due to its well-characterized role in the reticulocyte invasion....
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