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Genetic Diversity of Plasmodium vivax Cysteine-Rich Protective Antigen (PvCyRPA) in Field Isolates from Five Different Areas of the Brazilian Amazon.

Genes - 21 Oct 2021

Bitencourt Chaves Lana, Guimarães Glaucia de Oliveira, Perce-da-Silva Daiana de Souza, Banic Dalma Maria, Totino Paulo Renato Rivas, Machado Ricardo Luiz Dantas, Rodrigues-da-Silva Rodrigo Nunes, Pratt-Riccio Lilian Rose, Daniel-Ribeiro Cláudio Tadeu, Lima-Junior Josué da Costa

Abstract excerpt

The Plasmodium vivax Cysteine-Rich Protective Antigen (PvCyRPA) has an important role in erythrocyte invasion and has been considered a target for vivax malaria vaccine development. Nonetheless, its genetic diversity remains uncharted in Brazilian malaria-endemic areas. Therefore, we investigated the pvcyrpa genetic polymorphism in 98 field isolates from the Brazilian Amazon and its impact on the antigenicity of...

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Identifiers

PMID: 34828264
DOI: 10.3390/genes12111657
PMCID: PMC8623135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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