Article
Reduced polymorphism of Plasmodium vivax early transcribed membrane protein (PvETRAMP) 11.2.
Parasites & vectors - 17 Jul 2023
Perrotti Edvige, L'Episcopia Mariangela, Menegon Michela, Soares Irene S, Rosas-Aguirre Angel, Speybroeck Niko, LLanos-Cuentas Alejandro, Menard Didier, Ferreira Marcelo Urbano, Severini Carlo
Abstract excerpt
BACKGROUND: ETRAMP11.2 (PVX_003565) is a well-characterized protein with antigenic potential. It is considered to be a serological marker for diagnostic tools, and it has been suggested as a potential vaccine candidate. Despite its immunological relevance, the polymorphism of the P. vivax ETRAMP11.2 gene (pvetramp11.2) remains undefined. The genetic variability of an antigen may limit the effectiveness of its...
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