Diversity and natural selection in Plasmodium vivax Duffy binding protein gene.

doi:10.1016/s0166-6851(02)00327-4

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Article

Diversity and natural selection in Plasmodium vivax Duffy binding protein gene.

Molecular and biochemical parasitology - 3 Apr 2003

Cole-Tobian Jennifer, King Christopher L

Abstract excerpt

The Plasmodium vivax Duffy binding protein (DBP) binds to the Duffy blood group antigen on the surface of erythrocytes and is essential for invasion. Natural immunity develops to this protein making it an important vaccine candidate. Genetic diversity within and between populations was compared in 100 dbp sequences from isolates obtained from Papua New Guinea, Colombia, and South Korea. The cysteine-rich region...

Topics

Alleles
Amino Acid Sequence
Animals
Antigens, Protozoan
Base Sequence
Binding Sites
Duffy Blood-Group System
Genetic Variation
Phylogeny
Plasmodium
Plasmodium vivax

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Protein Binding

Protozoan Proteins

Receptors, Cell Surface

Selection, Genetic

Sequence Alignment

Source

Open in PubMed

Identifiers

PMID: 12672521
DOI: 10.1016/s0166-6851(02)00327-4

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12672521-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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