Article
D-Loop Mutations as Prognostic Markers in Glioblastoma-A Pilot Study.
International journal of molecular sciences - 14 Apr 2024
Szmyd Bartosz, Stanisławska Patrycja, Podstawka Małgorzata, Zaczkowski Karol, Izbiński Patryk M, Kulczycka-Wojdala Dominika, Stawski Robert, Wiśniewski Karol, Janczar Karolina, Braun Marcin, Białasiewicz Piotr, Jaskólski Dariusz J, Bobeff Ernest J
Abstract excerpt
Glioblastoma, a highly aggressive brain tumor, poses significant treatment challenges. A deeper investigation into its molecular complexity is essential for the identification of novel prognostic biomarkers and therapeutic strategies, potentially improving patient outcomes in terms of survival and quality of life. While nuclear DNA mutations have been extensively studied, the role of mitochondrial DNA (mtDNA)...
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