Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The identification of mitochondrial DNA variants in glioblastoma multiforme.

Acta neuropathologica communications - 2 Jan 2014

Yeung Ka Yu, Dickinson Adam, Donoghue Jacqueline F, Polekhina Galina, White Stefan J, Grammatopoulos Dimitris K, McKenzie Matthew, Johns Terrance G, St John Justin C

Abstract excerpt

BACKGROUND: Mitochondrial DNA (mtDNA) encodes key proteins of the electron transfer chain (ETC), which produces ATP through oxidative phosphorylation (OXPHOS) and is essential for cells to perform specialised functions. Tumor-initiating cells use aerobic glycolysis, a combination of glycolysis and low levels of OXPHOS, to promote rapid cell proliferation and tumor growth. Glioblastoma multiforme (GBM) is an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimetabolites
Share to Glioblastoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycolysis

Share to Heterografts

Share to Mitochondrial Proton-Translocating ATPases

Share to Neural Stem Cells

Share to Oxidative Phosphorylation

Share to Zalcitabine

Source

Open in PubMed Open full text

Identifiers

PMID: 24383468
DOI: 10.1186/2051-5960-2-1
PMCID: PMC3912901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The identification of mitochondrial DNA variants in glioblastoma multiforme.PMID 24383468Read ↗

Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma.Semantic proximity Read ↗

A comprehensive characterization of mitochondrial DNA mutations in glioblastoma multiforme.Semantic proximity Read ↗

Somatic Mutations in Nuclear and Mitochondrial Genes of Mitochondrial Proteins in Primary and Recurrent Glioblastoma.Semantic proximity Read ↗

Glioma grade and mortality in relation to sequence variation in the mitochondrial genome.Semantic proximity Read ↗

Mitochondrial DNA copy number alterations: Key players in the complexity of glioblastoma (Review)Semantic proximity Read ↗

Mitochondrial DNA Alterations in Glioblastoma and Current Therapeutic Targets.Semantic proximity Read ↗

Mitochondrial DNA Alterations in Glioblastoma (GBM).Semantic proximity Read ↗

Somatic mitochondrial DNA mutations in different grades of glioma.Semantic proximity Read ↗

Mitochondrial DNA copy number changes, heteroplasmy, and mutations in plasma-derived exosomes and brain tissue of glioblastoma patients.Semantic proximity Read ↗

D-Loop Mutations as Prognostic Markers in Glioblastoma-A Pilot Study.Semantic proximity Read ↗

The interplay of mitochondrial dysfunction and altered metabolic pathways in glioblastomaSemantic proximity Read ↗

Genetic association between mitochondrial DNA copy number and glioma risk: insights from causality.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.