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Article

Alternative polyadenylation quantitative trait loci contribute to acute myeloid leukemia risk genes regulation.

Leukemia research - 1 Jun 2024

Hu Xi, Cao Panxiang, Wang Fang, Wang Tong, Duan Junbo, Chen Xue, Ma Xiaoli, Zhang Yang, Chen Jiaqi, Liu Hongxing, Zhang Huqin, Wu Xiaoming

Abstract excerpt

Acute myeloid leukemia (AML) is a hematopoietic malignancy with a high relapse rate and progressive drug resistance. Alternative polyadenylation (APA) contributes to post-transcriptional dysregulation, but little is known about the association between APA and AML. The APA quantitative trait locus (apaQTL) is a powerful method to investigate the relationship between APA and single nucleotide polymorphisms (SNPs)....

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Source

Identifiers

PMID: 38640632
DOI: 10.1016/j.leukres.2024.107499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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