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Optimized cytogenetic risk-group stratification of KMT2A -rearranged pediatric acute myeloid leukemia

15 Apr 2024

Abstract excerpt

ABSTRACT: A comprehensive international consensus on the cytogenetic risk-group stratification of KMT2A-rearranged (KMT2A-r) pediatric acute myeloid leukemia (AML) is lacking. This retrospective (2005-2016) International Berlin-Frankfurt-Münster Study Group study on 1256 children with KMT2A-r AML aims to validate the prognostic value of established recurring KMT2A fusions and additional cytogenetic aberrations...

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PMID: 38621200
DOI: 10.1182/bloodadvances.2023011771

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