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Article

Control of false discoveries in grouped hypothesis testing for eQTL data.

BMC bioinformatics - 11 Apr 2024

Rudra Pratyaydipta, Zhou Yi-Hui, Nobel Andrew, Wright Fred A

Abstract excerpt

BACKGROUND: Expression quantitative trait locus (eQTL) analysis aims to detect the genetic variants that influence the expression of one or more genes. Gene-level eQTL testing forms a natural grouped-hypothesis testing strategy with clear biological importance. Methods to control family-wise error rate or false discovery rate for group testing have been proposed earlier, but may not be powerful or easily apply to...

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Identifiers

PMID: 38605284
DOI: 10.1186/s12859-024-05736-3
PMCID: PMC11007981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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