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Article

Robust Linear Models for Cis-eQTL Analysis.

PloS one - 1 Jan 2015

Rantalainen Mattias, Lindgren Cecilia M, Holmes Christopher C

Abstract excerpt

Expression Quantitative Trait Loci (eQTL) analysis enables characterisation of functional genetic variation influencing expression levels of individual genes. In outbread populations, including humans, eQTLs are commonly analysed using the conventional linear model, adjusting for relevant covariates, assuming an allelic dosage model and a Gaussian error term. However, gene expression data generally have noise...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25992607
DOI: 10.1371/journal.pone.0127882
PMCID: PMC4436354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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