Article
Impact of Family History and Germline Genetic Risk Single Nucleotide Polymorphisms on Long-Term Outcomes of Favorable-Risk Prostate Cancer.
The Journal of urology - 1 Jun 2024
Rumpf Florian, Plym Anna, Vaselkiv Jane B, Penney Kathryn L, Preston Mark A, Kibel Adam S, Mucci Lorelei A, Salari Keyan
Abstract excerpt
PURPOSE: Family history and germline genetic risk single nucleotide polymorphisms (SNPs) have been separately shown to stratify lifetime risk of prostate cancer. Here, we evaluate the combined prognostic value of family history of prostate and other related cancers and germline risk SNPs among patients with favorable-risk prostate cancer. MATERIALS AND METHODS: A total of 1367 participants from the prospective...
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