Genetic variants and family history predict prostate cancer similar to prostate-specific antigen.

doi:10.1158/1078-0432.CCR-08-1743

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Article

Genetic variants and family history predict prostate cancer similar to prostate-specific antigen.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2009

Zheng S Lilly, Sun Jielin, Wiklund Fredrik, Gao Zhengrong, Stattin Pär, Purcell Lina D, Adami Hans-Olov, Hsu Fang-Chi, Zhu Yi, Adolfsson Jan, Johansson Jan-Erik, Turner Aubrey R, Adams Tamara S, Liu Wennuan, Duggan David, Carpten John D, Chang Bao-Li, Isaacs William B, Xu Jianfeng, Grönberg Henrik

Abstract excerpt

PURPOSE: Although prostate-specific antigen (PSA) is the best biomarker for predicting prostate cancer, its predictive performance needs to be improved. Results from the Prostate Cancer Prevention Trial revealed the overall performance measured by the areas under curve of the receiver operating characteristic at 0.68. The goal of the present study is to assess the ability of genetic variants as a PSA-independent...

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Identifiers

PMID: 19188186
DOI: 10.1158/1078-0432.CCR-08-1743
PMCID: PMC3187807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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