Article
Common genetic variants in prostate cancer risk prediction--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2012
Lindström Sara, Schumacher Fredrick R, Cox David, Travis Ruth C, Albanes Demetrius, Allen Naomi E, Andriole Gerald, Berndt Sonja I, Boeing Heiner, Bueno-de-Mesquita H Bas, Crawford E David, Diver W Ryan, Gaziano J Michael, Giles Graham G, Giovannucci Edward, Gonzalez Carlos A, Henderson Brian, Hunter David J, Johansson Mattias, Kolonel Laurence N, Ma Jing, Le Marchand Loïc, Pala Valeria, Stampfer Meir, Stram Daniel O, Thun Michael J, Tjonneland Anne, Trichopoulos Dimitrios, Virtamo Jarmo, Weinstein Stephanie J, Willett Walter C, Yeager Meredith, Hayes Richard B, Severi Gianluca, Haiman Christopher A, Chanock Stephen J, Kraft Peter
Abstract excerpt
BACKGROUND: One of the goals of personalized medicine is to generate individual risk profiles that could identify individuals in the population that exhibit high risk. The discovery of more than two-dozen independent single-nucleotide polymorphism markers in prostate cancer has raised the possibility for such risk stratification. In this study, we evaluated the discriminative and predictive ability for prostate...
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