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Article

Early onset prostate cancer has a significant genetic component.

The Prostate - 1 Feb 2012

Lange Ethan M, Salinas Claudia A, Zuhlke Kimberly A, Ray Anna M, Wang Yunfei, Lu Yurong, Ho Lindsey A, Luo Jingchun, Cooney Kathleen A

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) affects more than 190,000 men each year with ∼10% of men diagnosed at ≤55 years, that is, early onset (EO) PCa. Based on historical findings for other cancers, EO PCa likely reflects a stronger underlying genetic etiology. METHODS: We evaluated the association between EO PCa and previously identified single nucleotide polymorphisms (SNPs) in 754 Caucasian cases from the Michigan...

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Identifiers

PMID: 21538423
DOI: 10.1002/pros.21414
PMCID: PMC3784829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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