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Article

Genetic variations in DNA excision repair pathway contribute to the chemosensitivity and prognosis of acute myeloid leukemia.

Clinica chimica acta; international journal of clinical chemistry - 15 May 2024

Zhang Amin, Liu Wancheng, Guo Xiaodong, Jia Hexiao, Wei Yihong, Can Can, He Na, Ji Chunyan, Ma Daoxin

Abstract excerpt

Acute myeloid leukemia (AML) is a hematologic malignancy with a high recurrence rate and poor long-term prognosis. DNA excision repair systems, such as base excision repair (BER) and nucleotide excision repair (NER), play a major role in maintaining genomic stability and integrity. Further intensive investigations are necessary to uncover additional AML prognosis loci. In this study, we analyzed 16 candidate SNPs...

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Identifiers

PMID: 38574942
DOI: 10.1016/j.cca.2024.117899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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