Article
Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia.
International journal of cancer - 1 Jan 2011
Shi Jing-Yi, Ren Zhi-Hong, Jiao Bo, Xiao Run, Yun Hai-Yang, Chen Bing, Zhao Wei-Li, Zhu Qi, Chen Zhu, Chen Sai-Juan
Abstract excerpt
Common genetic variations in genes involved in DNA repair or response to genotoxic stress may influence both cancer susceptibility and treatment response individually or interactively. However, in acute myeloid leukemia (AML), the relevance of these genetic variations remains to be fully established. In this study, we analyzed 42 genetic variations among 15 candidate genes in 307 AML patients and 560 age-sex...
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