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Article

DNA Repair Genes Polymorphisms: Impact on Acute Myeloid Leukemia Patients Outcome.

Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2022

Aref Salah, El Menshawy Nadia, Abou Zeid Tarek, Gouda Enas, Abdel Aziz Nora

Abstract excerpt

BACKGROUND: ATM; XRCC6 and LIG4 genes play an important role in repairing the double-strand DNA breaks and maintaining the genome stability. Single nucleotide polymorphisms (SNPs) in these genes could affect these genes expression and function. The aim of this study was to address the effect of SNP of the DNA repairing genes on corresponding gene expression as well as AML patient's outcome. SUBJECTS AND METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36308385
DOI: 10.31557/APJCP.2022.23.10.3577
PMCID: PMC9924318

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