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Article

Genetic variants of nucleotide excision repair pathway and outcomes of induction therapy in acute myeloid leukemia.

Personalized medicine - 1 Nov 2019

Sharifi Zohreh, Faranoush Mohammad, Mohseni Alireza, Rostami Shahrbano, Ramzi Mani, Sharifi Mohammad J

Abstract excerpt

Aim: Acute myeloid leukemia (AML) is a heterogeneous disease in pathogenesis and response to therapy. Nucleotide excision repair (NER) pathway has a major role in the elimination of genotoxic effects of chemotherapeutic agents. We aimed to clarify the effects of selected variants of XPD, XPC, ERCC5 and ERCC1 genes on the outcomes of induction therapy. Materials & methods: The prevalence of NER genetic variants...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 31647372
DOI: 10.2217/pme-2018-0077
PMCID: PMC7677594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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