Article
Polymorphisms in XPC provide prognostic information in acute myeloid leukemia.
International journal of hematology - 1 Oct 2012
Xu Peipei, Chen Baoan, Feng Jifeng, Cheng Lu, Xia Guohua, Li Yufeng, Qian Jun, Ding Jiahua, Lu Zuhong
Abstract excerpt
Acute myeloid leukemia (AML) is the most common type of adult leukemia for which cytosine arabinoside-based chemotherapy is the main treatment. Single nucleotide polymorphisms within the nucleotide excision repair pathway may alter the susceptibility of leukemia cells to chemotherapy. We investigated the roles of six single nucleotide polymorphisms (ERCC5rs76871136, ERCC5rs77569659, ERCC5rs873601, XPCrs2228000,...
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