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Article

XRCC1 Arg194Trp and Arg399Gln polymorphisms are significantly associated with shorter survival in acute myeloid leukemia.

Leukemia & lymphoma - 1 Feb 2014

Bănescu Claudia, Duicu Carmen, Trifa Adrian P, Dobreanu Minodora

Abstract excerpt

In the base excision repair pathway, the predominant DNA damage repair mechanism, X-ray repair cross-complementing group 1 (XRCC1) gene, has a crucial role. Defects in repair pathways are involved in cancer pathogenesis. Therefore, DNA repair genes might be involved in acute myeloid leukemia (AML) susceptibility. Our study aimed to evaluate the relationship between XRCC1 Arg194Trp, Arg280His and Arg399Gln...

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Identifiers

PMID: 23662987
DOI: 10.3109/10428194.2013.802781

Genes

XRCC1

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XRCC1 Arg194Trp and Arg399Gln polymorphisms are significantly associated with shorter survival in acute myeloid leukemia.PMID 23662987Read ↗

Genetic polymorphisms of XRCC1 and leukemia risk: a meta-analysis of 19 case-control studies.Semantic proximity Read ↗

XRCC1 Arg399Gln and Arg194Trp polymorphisms in childhood acute lymphoblastic leukemia risk: a meta-analysis.Semantic proximity Read ↗

The Arg399Gln polymorphism in the XRCC1 gene is associated with increased risk of hematological malignancies.Semantic proximity Read ↗

XRCC1 Arg399Gln variation and leukemia susceptibility: evidence from 2,647 cases and 5,518 controls.Semantic proximity Read ↗

XRCC3 Thr241Met polymorphism and risk of acute myeloid leukemia in a Romanian population.Semantic proximity Read ↗

X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and risk of childhood acute lymphoblastic leukemia: a meta-analysis.Semantic proximity Read ↗

Analysis of the polymorphisms XRCC1Arg194Trp and XRCC1Arg399Gln in gliomas.Semantic proximity Read ↗

Association between the XRCC1 polymorphisms and glioma risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

XRCC1 polymorphisms and cancer risk: a meta-analysis of 38 case-control studies.Semantic proximity Read ↗

Comprehensive assessment of the association between DNA repair gene XRCC3 Thr241Met polymorphism and leukemia risk.Semantic proximity Read ↗

Effect of XRCC1 Arg399Gln Gene Polymorphism on Survival in Lymphoblastic Leukemia.Semantic proximity Read ↗

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