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Article

Association between OGG1 S326C CC genotype and elevated relapse risk in acute myeloid leukemia.

International journal of hematology - 1 Sept 2018

Gotoh Nanami, Saitoh Takayuki, Takahashi Noriyuki, Kasamatsu Tetsuhiro, Minato Yusuke, Lobna Alkebsi, Oda Tsukasa, Hoshino Takumi, Sakura Toru, Shimizu Hiroaki, Takizawa Makiko, Handa Hiroshi, Yokohama Akihiko, Tsukamoto Norifumi, Murakami Hirokazu

Abstract excerpt

Recent studies have shown that tumors of relapsed acute myeloid leukemia (AML) present additional genetic mutations compared to the primary tumors. The base excision repair (BER) pathway corrects oxidatively damaged mutagenic bases and plays an important role in maintaining genetic stability. The purpose of the present study was to investigate the relationship between BER functional polymorphisms and AML relapse....

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Source

Identifiers

PMID: 29737460
DOI: 10.1007/s12185-018-2464-9

Genes

OGG1
XRCC1
MUTYH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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