Article
Causal role of lipid metabolome on the risk of ischemic stroke, its etiological subtypes, and long-term outcome: A Mendelian randomization study.
Atherosclerosis - 1 Dec 2023
Martín-Campos Jesús M, Cárcel-Márquez Jara, Llucià-Carol Laia, Lledós Miquel, Cullell Natàlia, Muiño Elena, Gallego-Fabrega Cristina, Fernández-Cadenas Israel
Abstract excerpt
BACKGROUND AND AIMS: The lipid profile is consistently associated with coronary artery disease (CAD) and ischemic stroke (IS). However, the lipoprotein subfractions have not been deeply explored in stroke subtypes, especially in IS outcome. METHODS: We performed two-sample Mendelian randomization (MR) analysis using 92 lipid traits measured by nuclear magnetic resonance in 115,000 subjects from the UK Biobank....
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