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Article

Genetically predicted small dense low-density lipoprotein cholesterol and ischemic stroke subtype: multivariable Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Yu Xiao, Shen Guangxun, Zhang Yan, Cui Cancan, Zha Yining, Li Pingan, Li Lihong, Wang Xu, Nan Guangxian

Abstract excerpt

Purpose: Small dense low-density lipoprotein cholesterol (S-LDL-C) has been suggested as a particularly atherogenic factor for ischemic stroke (IS) in observational studies, but the causality regarding the etiological subtype remains unclear. This study aims to explore the causal effects of small dense low-density lipoprotein cholesterol (S-LDL-C), medium (M-LDL-C) and large (L-LDL-C) subfractions on the lifetime...

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Share to Cholesterol, LDL
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

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Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 39135627
DOI: 10.3389/fendo.2024.1404234
PMCID: PMC11317295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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