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Article

High prevalence of "non-pathogenic" POLE mutation with poor prognosis in a cohort of endometrial cancer from South India.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Sept 2024

Kuriakose Santhosh, Dhanasooraj Dhananjayan, Shiny P M, Shammy S, Sona V P, Manjula Anupama A, Ramachandran Amrutha, Vijaykumar Bindu, Susan Nayana, Dinesan M, Sankar Uma V, Ramachandran Kavitha, Sreedharan P S

Abstract excerpt

OBJECTIVE: The Cancer Genome Atlas (TCGA) project identified favorable prognosis regarding the ultra-mutated endometrial cancer (EC) subtype linked to polymerase epsilon gene (POLE) mutations. This study investigated POLE mutations in EC of Indian patients. METHODS: This retrospective analytical study was conducted between January 2016 and January 2023 at the Government Medical College, Kozhikode, and the MVR...

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PMID: 38571325
DOI: 10.1002/ijgo.15486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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