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Article

DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells.

Mutagenesis - 1 Jan 2008

Mechilli Manuela, Schinoppi Angelo, Kobos Katarzyna, Natarajan Adayapalam T, Palitti Fabrizio

Abstract excerpt

Induction of chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) by acetaldehyde (AA) was evaluated in parental and different DNA repair-deficient Chinese hamster ovary (CHO) cell lines to elucidate the mechanisms involved in the protection against AA-induced chromosome damage. Cell lines employed included the parental (AA8), nucleotide excision repair (UV4, UV5, UV61), base excision repair (EM9),...

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PMID: 17989147
DOI: 10.1093/mutage/gem042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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