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Protein Kinase A in neurological disorders

13 Mar 2024

Abstract excerpt

Cyclic adenosine 3', 5' monophosphate (cAMP)-dependent Protein Kinase A (PKA) is a multi-functional serine/threonine kinase that regulates a wide variety of physiological processes including gene transcription, metabolism, and synaptic plasticity. Genomic sequencing studies have identified both germline and somatic variants of the catalytic and regulatory subunits of PKA in patients with metabolic and...

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PMID: 38481146
DOI: 10.1186/s11689-024-09525-0

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