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Article

Genetic variation drives differences in obesity-related gene regulation.

Trends in genetics : TIG - 1 Apr 2024

Kaikkonen Minna U

Abstract excerpt

Heikkinen and colleagues recently demonstrated that genetic variation, rather than dietary changes, governs gene regulation in liver. This finding highlights the impact of noncoding variants on chromatin accessibility, histone modifications, transcription factor binding, and gene expression and has implications for future research directions in understanding the genetic basis of disease.

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Source

Identifiers

PMID: 38462400
DOI: 10.1016/j.tig.2024.02.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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