Article

Expanded Chromatin Accessibility Mapping Explains Genetic Variation Associated with Complex Traits in Liver

2025-09-15

Abstract excerpt

Genome-wide association studies (GWAS) have identified thousands of loci associated with a variety of common, complex human traits. Recent efforts have focused on characterizing chromatin accessibility to discover regulatory elements that modify the expression of nearby genes, suggesting that trait associations are mediated through changes in gene regulation. Genetic variants associated with differences in chromat...

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Literature Corpus work: 7695341e-7dba-5505-beda-bae88f43b167
DOI: 10.1101/2025.09.15.25335593

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