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Article

Taking the risk. A systematic review of ethical reasons and moral arguments in the clinical use of polygenic risk scores.

American journal of medical genetics. Part A - 1 Jul 2024

Andreoli Lara, Peeters Hilde, Van Steen Kristel, Dierickx Kris

Abstract excerpt

Debates about the prospective clinical use of polygenic risk scores (PRS) have grown considerably in the last years. The potential benefits of PRS to improve patient care at individual and population levels have been extensively underlined. Nonetheless, the use of PRS in clinical contexts presents a number of unresolved ethical challenges and consequent normative gaps that hinder their optimal implementation....

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Identifiers

PMID: 38450933
DOI: 10.1002/ajmg.a.63584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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