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Ethical, Legal and Social Implications of Polygenic Scores for Multifactorial Disease: A Narrative Review Identifying Concerns About Interpretation and Use

2022-09-16

Abstract excerpt

Advances in genomics have enabled the development of polygenic scores (PGS), sometimes called polygenic risk scores, in the context of multifactorial traits and diseases such as height, cancer, cardiovascular disease, and mental illness. PGS are measures of an individual’s genetic predisposition, as compared to other members of a population, for conditions which are influenced by both genetic and environmental fac...

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Literature Corpus work: fb10a714-4944-56fb-ba75-4ebb2c07e6ff
DOI: 10.21203/rs.3.rs-2022716/v1

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