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Epigenome editing for targeted DNA (de)methylation: a new perspective in modulating gene expression

3 Mar 2024

Abstract excerpt

Traditionally, it has been believed that inheritance is driven as phenotypic variations resulting from changes in DNA sequence. However, this paradigm has been challenged and redefined in the contemporary era of epigenetics. The changes in DNA methylation, histone modification, non-coding RNA biogenesis, and chromatin remodeling play crucial roles in genomic functions and regulation of gene expression. More...

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PMID: 38440883
DOI: 10.1080/10409238.2024.2320659

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