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Epigenome editing by CRISPR/Cas9 in clinical settings: possibilities and challenges

15 Nov 2019

Abstract excerpt

Epigenome editing is a promising approach for both basic research and clinical application. With the convergence of techniques from different fields, regulating gene expression artificially becomes possible. From a clinical point of view, targeted epigenome editing by CRISPR/Cas9 of disease-related genes offers novel therapeutic avenues for many diseases. In this review, we summarize the EpiEffectors used in...

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PMID: 31819946
DOI: 10.1093/bfgp/elz035

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