Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study.

doi:10.1186/s12872-024-03765-7

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Article

Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study.

BMC cardiovascular disorders - 13 Feb 2024

Fransén Karin, Hiyoshi Ayako, Paramel Geena V, Hurtig-Wennlöf Anita

Abstract excerpt

BACKGROUND: The Caspase activation and recruitment domain 8 (CARD8) protein is a component of innate immunity as a negative regulator of NF- ĸB, and has been associated with regulation of proteins involved in inflammation. Expression of CARD8 mRNA and protein has been identified in human atherosclerotic lesions, and the truncated T30A variant (rs2043211) of CARD8 has been associated with lower C-reactive (CRP)...

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PMID: 38350853
DOI: 10.1186/s12872-024-03765-7
PMCID: PMC10863129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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