Article
Regulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.
Stroke - 1 Feb 2014
Bai Ying, Nie Shaofang, Jiang Guiqing, Zhou Yingchao, Zhou Mengchen, Zhao Yuanyuan, Li Sisi, Wang Fan, Lv Qiulun, Huang Yufeng, Yang Qin, Li Qingxian, Li Yue, Xia Yunlong, Liu Ying, Liu Jinqiu, Qian Jin, Li Bin, Wu Gang, Wu Yanxia, Wang Binbin, Cheng Xiang, Yang Yanzong, Ke Tie, Li Hui, Ren Xiang, Ma Xu, Liao Yuhua, Xu Chengqi, Tu Xin, Wang Qing K
Abstract excerpt
BACKGROUND AND PURPOSE: ANRIL has long been considered as the strongest candidate gene at the 9p21 locus, robustly associated with stroke and coronary artery disease. However, the underlying molecular mechanism remains unknown. The present study works to elucidate such a mechanism. METHODS: Using expression quantitative loci analysis, we identified potential genes whose expression may be influenced by genetic...
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