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Article

The P124A mutation of SRP14 alters its migration on SDS-PAGE without impacting its function.

Acta biochimica et biophysica Sinica - 25 Feb 2024

Liu Yaofu, Zhou Jinqiu

Abstract excerpt

SRP14 is a crucial protein subunit of the signal recognition particle (SRP), a ribonucleoprotein complex essential for co-translational translocation to the endoplasmic reticulum. During our investigation of SRP14 expression across diverse cell lines, we observe variations in its migration on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), with some cells exhibiting slower migration and...

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Identifiers

PMID: 38273782
DOI: 10.3724/abbs.2024004
PMCID: PMC10984872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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