Article

Role of the novel endoribonuclease SLFN14 and its disease causing mutations in ribosomal degradation

2018-02-18

Abstract excerpt

<h4>ABSTRACT</h4> Platelets are anucleate and mostly ribosome-free cells within the bloodstream, derived from megakaryocytes within bone marrow and crucial for cessation of bleeding at sites of injury. Inherited thrombocytopenias are a group of disorders characterized by alow platelet count and are frequently associated with excessive bleeding. SLFN14 is one of the most recently discovered genes linked to inheri...

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Literature Corpus work: a9485710-549f-5cb6-b955-bbcc98be691b
DOI: 10.1101/267633

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