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Article

Phosphorylation of Y14 modulates its interaction with proteins involved in mRNA metabolism and influences its methylation.

The Journal of biological chemistry - 14 Oct 2005

Hsu Ia-Wen, Hsu Min, Li Chin, Chuang Tzu-Wei, Lin Ru-Inn, Tarn Woan-Yuh

Abstract excerpt

The multicomponent exon junction complex (EJC) is deposited on the spliced mRNA during pre-mRNA splicing and is implicated in several post-splicing events, including mRNA export, nonsense-mediated mRNA decay (NMD), and translation control. This report is the first to identify potential post-translational modifications of the EJC core component Y14. We demonstrate that Y14 is phosphorylated at its repeated...

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Identifiers

PMID: 16100109
DOI: 10.1074/jbc.M507658200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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