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Article

Molecular evolution of SRP cycle components: functional implications.

Nucleic acids research - 11 Jun 1994

Althoff S, Selinger D, Wise J A

Abstract excerpt

Signal recognition particle (SRP) is a cytoplasmic ribonucleoprotein that targets a subset of nascent presecretory proteins to the endoplasmic reticulum membrane. We have considered the SRP cycle from the perspective of molecular evolution, using recently determined sequences of genes or cDNAs encoding homologs of SRP (7SL) RNA, the Srp54 protein (Srp54p), and the alpha subunit of the SRP receptor (SR alpha) from...

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Identifiers

PMID: 7518075
DOI: 10.1093/nar/22.11.1933
PMCID: PMC308104

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