Article

Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24

2020-03-05

Abstract excerpt

Thousands of previously unannotated small and alternative open reading frames (alt-ORFs) have recently been revealed in the human genome, and hundreds are now known to be required for cell proliferation. Many alt-ORFs are co-encoded with proteins of known function in multicistronic human genes, but the functions of only a handful are currently known in molecular detail. Using a proteomic strategy for discovery of...

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Literature Corpus work: 7a2d51d4-5c7a-56e4-a2e2-a20b897bcdde
DOI: 10.1101/2020.03.04.977314

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