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Article

LIGHT/TNFSF14 Affects Adipose Tissue Phenotype.

International journal of molecular sciences - 5 Jan 2024

Oranger Angela, Colaianni Graziana, Ingravallo Giuseppe, Scarcella Vincenza Sara, Faienza Maria Felicia, Grano Maria, Colucci Silvia, Brunetti Giacomina

Abstract excerpt

LIGHT/TNFSF14 is linked to several signaling pathways as a crucial member of a larger immunoregulatory network. It is primarily expressed in inflammatory effector cells, and high levels of LIGHT have been reported in obesity. Thus, with the aim of deepening the knowledge of the role of LIGHT on adipose tissue phenotype, we studied wild-type (WT), Tnfsf14-/-, Rag-/- and Rag-/Tnfsf14- (DKO) mice fed a normal diet...

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Identifiers

PMID: 38255789
DOI: 10.3390/ijms25020716
PMCID: PMC10815871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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