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Article

High fat intake induces a population of adipocytes to co-express TLR2 and TNFalpha in mice with insulin resistance.

Biochemical and biophysical research communications - 16 Mar 2007

Murakami Kentaro, Bujo Hideaki, Unoki Hiroyuki, Saito Yasushi

Abstract excerpt

Cytokine production in fat tissue plays a key role in insulin resistance. The aim of study is to know the phenotypic changes of adipocytes with high fat-induced insulin resistance. High fat intake induced the expression of tumor necrosis factor alpha (TNFalpha) in visceral fat tissue as well as development of insulin resistance. Analysis of the gene expression profiles in adipocytes showed that high fat intake...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17266936
DOI: 10.1016/j.bbrc.2007.01.039

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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