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Article

The relationship between body weight and inflammation: Lesson from anti-TNF-α antibody therapy.

Human immunology - 1 Jan 2016

Peluso Ilaria, Palmery Maura

Abstract excerpt

Obesity is associated with many pathological conditions. Tumor Necrosis Factor-α (TNF-α) is one of the key mediators of inflammation involved in the obesity-related insulin resistance development. We aim to review the human evidence useful to clarify the relationship between inflammation and body weight, with particular reference to TNF-α. Genetic polymorphisms and epigenetic factors, such as diet, could affect...

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Identifiers

PMID: 26472017
DOI: 10.1016/j.humimm.2015.10.008

Genes

TNF

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