Article

Adipose Tissue Caveolin-1 Upregulation in Obesity Involves TNF-α/NFκB Mediated Signaling.

2022-12-12

Abstract excerpt

Obesity is characterized by chronic low-grade inflammation. Caveolin-1 (CAV1), a structural and functional protein found in adipose tissues (AT), is augmented in obese individuals. We aimed to define the inflammatory mediators that influence CAV1 gene regulation and associated mechanism in obesity. Using subcutaneous AT from 27 (7 lean/20 obese) normoglycemic individuals, in vitro human adipocyte models, and in vi...

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Literature Corpus work: 4027ede7-11c9-58cb-8536-e0cfaf0eeb24
DOI: 10.20944/preprints202212.0194.v1

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