Article
MRAS in coronary artery disease-Unchartered territory.
IUBMB life - 1 Jun 2024
Shah Pashmina Wiqar, Reinberger Tobias, Hashmi Satwat, Aherrahrou Zouhair, Erdmann Jeanette
Abstract excerpt
Genome-wide association studies (GWAS) have identified coronary artery disease (CAD) susceptibility locus on chromosome 3q22.3. This locus contains a cluster of several genes that includes muscle rat sarcoma virus (MRAS). Common MRAS variants are also associated with CAD causing risk factors such as hypertension, dyslipidemia, obesity, and type II diabetes. The MRAS gene is an oncogene that encodes a...
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