Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myocardin: A novel player in atherosclerosis.

Atherosclerosis - 1 Feb 2017

Xia Xiao-Dan, Zhou Zhen, Yu Xiao-Hua, Zheng Xi-Long, Tang Chao-Ke

Abstract excerpt

Myocardin (MYOCD) the most important coactivator of serum response factor (SRF), plays a critical role specifically in the development of cardiac myocytes and vascular smooth muscle cells (VSMCs). Binding of Myocardin to the SRF on the CArG box-containing target genes can transcriptionally activate a variety of downstream muscle-specific genes, such as Sm22α, Acta2, Myh11, and several other signaling pathways....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Cell Differentiation
Share to Muscle, Smooth, Vascular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Myocytes, Cardiac

Share to Myocytes, Smooth Muscle

Share to Nuclear Proteins

Share to Serum Response Factor

Share to Trans-Activators

Source

Identifiers

PMID: 28012646
DOI: 10.1016/j.atherosclerosis.2016.12.002

Genes

SRF
MYOCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myocardin: A novel player in atherosclerosis.PMID 28012646Read ↗

Myocardin in biology and diseaseSemantic proximity Read ↗

HERP1 Inhibits Myocardin-Induced Vascular Smooth Muscle Cell Differentiation by Interfering With SRF Binding to CArG BoxSemantic proximity Read ↗

Emerging roles of the myocardin family of proteins in lipid and glucose metabolismSemantic proximity Read ↗

Myocardin regulates vascular smooth muscle cell inflammatory activation and disease.Semantic proximity Read ↗

Myocardin is required for maintenance of vascular and visceral smooth muscle homeostasis during postnatal development.Semantic proximity Read ↗

Myocardin: a component of a molecular switch for smooth muscle differentiation.Semantic proximity Read ↗

Myocardin is a master regulator of smooth muscle gene expression.Semantic proximity Read ↗

Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes.Semantic proximity Read ↗

Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription FactorsSemantic proximity Read ↗

The serum response factor coactivator myocardin is required for vascular smooth muscle development.Semantic proximity Read ↗

Arp5 is a key regulator of myocardin in smooth muscle cells.Semantic proximity Read ↗

Long non-coding RNA CARDINAL cis-activates MYOCD expression by recruiting histone reader ZZZ3 in vascular smooth muscle cell phenotype alteration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.