Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics links between transforming growth factor β pathway and coronary disease.

Atherosclerosis - 1 Oct 2016

Zeng Lingyao, Dang Tan An, Schunkert Heribert

Abstract excerpt

Recent genome-wide association studies broadened our view on the complex genetic roots of coronary artery disease (CAD). The subsequent challenge is now to elucidate the mechanisms linking genetic variants with disease risk. Here, we focus on the transforming growth factor beta (TGF-β) pathway and review genetic as well as comprehensive annotation and systems biology analyses to provide further links between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Cardiovascular System
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Myocytes, Smooth Muscle

Share to Smad Proteins

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 27596813
DOI: 10.1016/j.atherosclerosis.2016.08.029

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics links between transforming growth factor β pathway and coronary disease.PMID 27596813Read ↗

Genetic Risk Factors Related to Coronary Artery Disease and Role of Transforming Growth Factor Beta 1 Polymorphisms.Semantic proximity Read ↗

Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease riskSemantic proximity Read ↗

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.Semantic proximity Read ↗

TGFβ Signaling and Cardiovascular DiseasesSemantic proximity Read ↗

Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci.Semantic proximity Read ↗

Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk lociSemantic proximity Read ↗

Polymorphisms of TGFβ-1 and TGFBR2 in relation to coronary artery disease in a Chinese population.Semantic proximity Read ↗

Genetic Insights into Coronary Heart Disease: A Multi-Omic ApproachSemantic proximity Read ↗

Functional interaction between COL4A1/COL4A2 and SMAD3 risk loci for coronary artery diseaseSemantic proximity Read ↗

Advances and Challenges for GWAS Analysis in Cardiac Diseases: A Focus on Coronary Artery Disease (CAD).Semantic proximity Read ↗

Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.Semantic proximity Read ↗

Exploring the genetic basis of coronary artery disease using functional genomics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.