Article
A Smooth Muscle Cell-Enriched Long Noncoding RNA Regulates Cell Plasticity and Atherosclerosis by Interacting With Serum Response Factor.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2021
Ni Huaner, Haemmig Stefan, Deng Yihuan, Chen Jingshu, Simion Viorel, Yang Dafeng, Sukhova Galina, Shvartz Eugenia, Wara A K M Khyrul, Cheng Henry S, Pérez-Cremades Daniel, Assa Carmel, Sausen Grasiele, Zhuang Rulin, Dai Qiuyan, Feinberg Mark W
Abstract excerpt
Objective: Vascular smooth muscle cell (VSMC) plasticity plays a critical role in the development of atherosclerosis. Long noncoding RNAs (lncRNAs) are emerging as important regulators in the vessel wall and impact cellular function through diverse interactors. However, the role of lncRNAs in regulating VSMCs plasticity and atherosclerosis remains unclear. Approach and Results: We identified a VSMC-enriched...
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