Article

Aging microenvironment: the critical factor to determine the prognosis of glioblastoma from the perspective of response to chemoradiotherapy and immunoregulation

2024-11-18

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM) is a highly aggressive brain tumor. With age, many factors in the microenvironment will change, and these changes have an important impact on tumor growth, development and treatment response. This study aims to investigate gene signatures and prognostic value of the aging microenvironment in GBM. The correlation between transcriptional data, clinical information, immu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e52e8b7d-dd40-509b-b48e-348f26bcf9f1
DOI: 10.21203/rs.3.rs-5289523/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Aging microenvironment: the critical factor to determine the prognosis of glioblastoma from the perspective of response to chemoradiotherapy and immunoregulationDOI 10.21203/rs.3.rs-5289523/v1Read

Identification of Key Genes and Signaling Pathways Associated with the Progression of Glioblastoma multiformSemantic proximity Read

Identification of Immune Cell Infiltration and Immune-Related Genes in the Tumor Microenvironment of GlioblastomasSemantic proximity Read

Functional implications of aging-related lncRNAs for predicting prognosis and immune status in glioma patientsSemantic proximity Read

Identification of an Immune-Related Prognostic Risk Model in GlioblastomaSemantic proximity Read

Glioblastoma as an age-related neurological disorder in adultsSemantic proximity Read

Identification of CXCL8, IL1A, and IL1B as Hub Genes of Therapeutic Resistance in Glioblastoma Multiforme via Bioinformatics AnalysisSemantic proximity Read

Comprehensive analysis and experiment of hypoxia and EMT-related genes in prognosis and immune response of glioblastomaSemantic proximity Read

Integrated Transcriptome Profiling Identifies Prognostic Hub Genes as Therapeutic Targets of Glioblastoma: Evidenced by Bioinformatics AnalysisSemantic proximity Read

Identification of an Immune-Related Prognostic Signature for Glioblastoma by Comprehensive Bioinformatics and Experimental AnalysesSemantic proximity Read

Bioinformatics analyses of significant genes, related pathways and candidate prognostic biomarkers in glioblastomaSemantic proximity Read

Characterization of the gene expression profile in younger and older low-grade glioma patientsSemantic proximity Read

Short Survival-Related Genes Harbor EMT Processes and Dendritic Cell Infiltration in GlioblastomaSemantic proximity Read