Article

Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference

2021-02-16

Abstract excerpt

<title>Abstract</title> <p>Glioblastomas are highly malignant tumors of the central nervous system. Evidence suggests that these tumors display large intra- and inter-patient heterogeneity hallmarked by subclonal diversity and dynamic adaptation amid developmental hierarchies. However, the source for dynamic reorganization of cellular states within their spatial context remains elusive. Here, we in-depth characte...

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Literature Corpus work: d6d36f41-32cc-5e6e-a68a-66ba229ea560
DOI: 10.21203/rs.3.rs-244902/v1

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